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The issue of the Down-Syndrome has not been clarified so far. Experts in the field say that Down it is a coincidence Down for Down-syndrome. Although various theses have been suggested about the determinants of Down Syndrome, such as maternal age, radiation, troit antibodies, drug and alcohol use, there is no definite one. As a result, chromosome 21 could not be divided for unknown reasons and remained in the new cell.
The maternal age is the only statistical data associated with the frequency of the syndrome. Recent studies have shown that chromosome indivisibility can be caused not only by the mother's egg but also by the father's sperm.
|AGE'S AGE||RISK OF DOWN SYNDROME|
|Under 20||One in 1700 births|
|20-25 years old||1350 births|
|25-30 years old||One in 1150 births|
|Between 30-35 years||One in 700 births|
|35-40 years old||Every 250 births|
|40-45 years old||One in 70 births|
|Over 45||16 births|
* Number of children with Down Syndrome compared to all births
What is the risk of subsequent children with Down's Syndrome?
The answer depends on the type of chromosome change in the child. The risk of recurrence after child birth is less than 1% in Trisomy 21. It does not depend on the age of the parents. In mosaic form, the risk is not high, but there are exceptions.